Biography:  Albert P. Li, Ph. D., MBA

 

Dr. Li is an internationally renowned expert in drug metabolism and toxicology.  The focus of his activities for the past 2 decades is on the development and validation of human-based in vitro experimental systems for the evaluation of human drug properties. Dr. Li’s current research emphasis is the application of human-based in vitro experimental systems in drug discovery and development.  His pioneering research on hepatocyte isolation, culturing and cryopreservation allows human and animal hepatocytes to be used routinely as a research tool.   Dr. Li and his colleagues have developed numerous human cell-based experimental systems for the evaluation of critical drug properties such as bioavailability, metabolic stability, toxicity and drug-drug interaction potential. Earlier in his career, Dr. Li was instrumental in the development of the mammalian genetic toxicology assay, CHO/HGPRT gene mutation assay, for industrial applications.  The assay is now one of the routine assays for the evaluation of the genotoxic potential of industrial chemicals, agricultural chemicals, and pharmaceuticals

 

Dr. Li is presently Founder, President and Chief Executive Officer of Advanced Pharmaceutical Sciences, Inc., a company recently founded by Dr. Li to develop novel technologies and approaches to accurate predict human drug properties.  Previously, Dr. Li was President and CEO of Phase 1 Molecular Toxicology, Inc. in Santa Fe, New Mexico, U. S. A. (2002-2003), Chief Scientific Officer of In Vitro Technologies, Inc., Baltimore, Maryland, U. S. A. (1995-2002); Research Professor and Director of the Surgical Research Institute, Department of Surgery, St. Louis University Medical School (1993-1995); Senior Fellow and Director, Liver Biology Department, Monsanto Company (1982 – 1993); Group Leader, Cellular and Genetic Toxicology, Lovelace Inhalation Toxicology Research Institute (1979 – 1982); Assistant Professor and Research Scientist, Cancer Research and Treatment Center and Department of Radiology, University of New Mexico (1976 – 1979).  Dr. Li obtained his B. Sc. (1972, Chemistry) from the University of Wisconsin, Stevens Point, and Ph. D. (1976, Biomedical Sciences) from the University of Tennessee, Oakridge Graduate School of Biomedical Sciences.  His received his doctoral training and performed his dissertation research under Professor Abraham Hsie in the Biology Division of Oak Ridge National Laboratory, Oak Ridge, Tennessee.

 

Dr. Li is an active member of the scientific community. He edited 5 books and published over 100 peer-reviewed papers.  He serves as Editor, Hepatocyte Reports for the journal Chemico-Biological Interactions and is on the editorial board of the journal Cell Biology and Toxicology.